The computational search for promoters is an attractive problem in the field of sequence analysis. In a bacterial genome, the transcription start site (TSS) is chosen mostly by the sigma (σ) factors while the architecture of the promoter itself exerts σ specificity.
bTSSfinder is a software tool that predicts putative prompters for five classes of sigma factors in E. coli (σ70, σ38, σ32, σ28 and σ24) and in Cyanobacteria (σA, σC, σH, σG and σF). bTSSfinder also classifies cyanobacterial promoters. bTSSfinder achieves high accuracy and has a broad scope of application.
Program bTSSfinder was developed in Computational Bioscience Research Center (King Abdullah University of Science and Technology, Kingdom of Saudi Arabia)