1. What is DDPC?
DDPC (Dragon Database of Genes Implicated in Prostate Cancer) is a knowledgebase of genes experimentally verified to be involved in prostate cancer (PC).

2. Why DDPC was created?
DDPC was created to provide students, researchers and medical practitioners with enriched information on genes involved in PC.

3. What are the benefits of using DDPC?
DDPC provides gene-associated data such as protein annotation, molecular pathways, ontologies and transcription regulation. It enables biologist to circumvent the large amount of energy and time spent in analyzing pertinent biological problems involving PC.

4. What is unique about DDPC, which cannot be found in any other cancer database?
To the best of our knowledge there is no single comprehensive, web based resource that has integrated data solely on genes experimentally verified to be involved in PC. It contains information on pre-compiled literature based text-mining report, transcription factor binding sites, drug and drug targets, and molecular pathways.

5. Does this database represent all genes associated with PC?
Certainly not, this database contains genes implicated in PC through experimental verification. The gene list would be expanded in the next round of update.

6. Can I extract the information provided in the database for a particular gene?
Yes, you can download the information about the list of transcription factors having binding sites in the promoters of genes and associated functional annotation in the "CSV" format. The text-mining reports can also be downloaded for future usage.

7. Are there any other modifications or additions in the pipeline?
Yes, we would like to expand this database by incorporating information about differentially expressed genes in PC as detected via high-throughput techniques such as microarrays. Data on protein protein interactions associated with PC would be integrated into this database.

8. Is there a tutorial manual on DDPC?
Yes, a tutorial manual has been developed to ease the exploration of this database and can be downloaded by clicking on the download menu.

9. Does DDPC contains information on PC drugs?
Useful information on drug targets and drugs associated with PC have been integrated via DrugBank.

10. To whom can I report a bug or discrepancy?
Please refer all queries via: monique@sanbi.ac.za

© 2010-2017 All rights reserved. King Abdullah University of Science and Technology, All rights reserved