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Dictionaries: Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Human Genes+Proteins ( 0 1 2 3 4 5 6 7 8 9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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C

CXCL8 -> 
  
CCL2 [1]   CXCL1 [1]   FGR [1]   GELATINASE B [1]   HCK [1]   MIP-2 [1]   NF-KAPPAB [1]   SRC [1]   VASCULAR ENDOTHELIAL GROWTH FACTOR [1]   VEGF-A [1]   CHEMOKINE [2]  
INFLAMMATION [1]   KAPOSI'S SARCOMA [1]   TRANSLOCATION [1]   TUMOUR [1]   VASCULARISATION [1]   ANGIOGENESIS [2]  
ACTIVATE [1]   ASSOCIATED [1]   CONTROL [1]   INDUCE [1]   INHIBIT [1]   INHIBITED [1]   INHIBITOR [1]   KINASE [1]   MEDIATED [1]   PREVENT [1]   RECRUITMENT [1]   REDUCED [1]   REPRESSES [1]   STIMULATION [1]   INDUCED [2]  

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CXCL9 -> 
  
CHEMOKINE [1]   CHEMOKINE RECEPTOR [1]   CXCL10 [1]   CXCL11 [1]   CXCR3 [1]   IP-10 [1]  
ATHEROSCLEROSIS [1]   MULTIPLE SCLEROSIS [1]   ORGAN TRANSPLANTATION [1]  
ASSOCIATED [1]   BINDING [1]   BLOCK [1]   BLOCKING [1]   INHIBITOR [1]   INTERACTION [1]   LIGAND [1]   PRODUCT [1]   RECRUITMENT [1]  

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CXCR1 -> 
  
CXCR2 [1]   IL-8 [1]   IL-8 RECEPTOR [1]   L1.2 [1]   TNF [1]  
ACUTE [1]   ANGIOGENESIS [1]   CHRONIC [1]   CHRONIC INFLAMMATORY DISEASE [1]   INFILTRATION [1]   INFLAMMATION [1]   INJURY [1]   LIVER ISCHAEMIA [1]  
SIGNAL TRANSDUCTION [1]  
ALLOSTERIC [1]   ASSOCIATED [1]   BINDING [1]   BLOCKING [1]   DECREASED [1]   INFLUX [1]   INHIBITED [1]   INHIBITOR [1]   INTERACTION [1]   LIGAND [1]   PREVENTED [1]   PRODUCTION [1]   REDUCED [1]  

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CXCR2 -> 
  
CXCR1 [1]   IL-8 [1]   IL-8 RECEPTOR [1]   L1.2 [1]   TNF [1]  
ACUTE [1]   ANGIOGENESIS [1]   CHRONIC [1]   CHRONIC INFLAMMATORY DISEASE [1]   INFILTRATION [1]   INFLAMMATION [1]   INJURY [1]   LIVER ISCHAEMIA [1]  
SIGNAL TRANSDUCTION [1]  
ALLOSTERIC [1]   ASSOCIATED [1]   BINDING [1]   BLOCKING [1]   DECREASED [1]   INFLUX [1]   INHIBITED [1]   INHIBITOR [1]   INTERACTION [1]   LIGAND [1]   PREVENTED [1]   PRODUCTION [1]   REDUCED [1]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


CXCR3 -> 
  
CHEMOKINE [1]   CHEMOKINE RECEPTOR [1]   CXCL10 [1]   CXCL11 [1]   CXCL9 [1]   IP-10 [1]  
ATHEROSCLEROSIS [1]   MULTIPLE SCLEROSIS [1]   ORGAN TRANSPLANTATION [1]  
ASSOCIATED [1]   BINDING [1]   BLOCK [1]   BLOCKING [1]   INHIBITOR [1]   INTERACTION [1]   LIGAND [1]   PRODUCT [1]   RECRUITMENT [1]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


CXCR4 -> 
  
BMP-2 [1]   CHEMOKINE [1]   CHEMOKINE RECEPTOR [1]   CXCL2 [1]   IGF-1 [1]   SDF-1 [1]   VEGF [1]  
BIPHASIC [1]   INFILTRATION [1]   TENDON INJURY [1]  
AFFECT [1]   CONTROL [1]   EFFECT [1]   ENHANCE [1]   ENHANCED [1]   INCREASE [1]   INDUCE [1]   INDUCED [1]   PRODUCTION [1]   RECRUITMENT [1]   REDUCE [1]   STIMULATION [1]   EXPRESSION [2]   INCREASED [2]  

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CYCLIC NUCLEOTIDE PHOSPHODIESTERASE -> 
  
CALMODULIN [1]   MYOSIN [1]   PDE [1]   PDE3 [1]   PDE4 [1]  
ERYTHROCYTE [1]   GUINEA [1]   TAENIA [1]  
OKADAIC ACID [1]  
ACTIVATE [1]   ACTIVATED [1]   ACTIVATION [1]   ACTIVATOR [1]   CAUSED [1]   EFFECT [1]   INCREASED [1]   INDUCED [1]   KINASE [1]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


CYCLIN -> 
  
BCL-2 [1]   BCR [1]   BIS [1]   CASEIN KINASE 1 [1]   CASPASE-3 [1]   CDC25C [1]   CDK-4 [1]   CDK6 [1]   CDK7 [1]   CELL CYCLE REGULATORY PROTEIN [1]   CIAP-2 [1]   CK1 [1]   CRKL [1]   CYCLIN A [1]   CYCLIN B1 [1]   CYTOCHROME C [1]   DBH [1]   DR4 [1]   FAS [1]   GLYCOGEN SYNTHASE KINASE [1]   GLYCOPHORIN A [1]   GSK-3BETA [1]   HDAC [1]   HTERT [1]   MAP KINASE [1]   MAP-1B [1]   MPF [1]   NRK [1]   P-GLYCOPROTEIN [1]   P16 [1]   P27KIP1 [1]   P56 [1]   PAK1 [1]   PCNA [1]   PGP [1]   PHOSPHOLIPASE C [1]   PI SYNTHASE [1]   PI4-KINASE [1]   POLY(ADP-RIBOSE) POLYMERASE [1]   PP2C-ALPHA [1]   PROLIFERATING CELL NUCLEAR ANTIGEN [1]   PROTEIN TAU [1]   PSA [1]   TRANSCRIPTION FACTOR E2F [1]   TUMOR NECROSIS FACTOR [1]   TYPE I PROCOLLAGEN [1]   WAF1 [1]   XIAP [1]   BAX [2]   CDC2 [2]   CDC25 [2]   CDC25A [2]   CDK1 [2]   CDK4 [2]   CDK5 [2]   GSK-3 [2]   IAP [2]   PLC [2]   PROTEIN KINASE [2]   PTX-2 [2]   TYROSINE KINASE [2]   CYCLIN D1 [3]   CYCLIN E [3]   P21 [5]   P53 [5]   PRB [6]   CDK2 [7]  
ADENOVIRUS [1]   ALCOHOL [1]   ALGAE [1]   CHRONIC INFLAMMATORY DISEASE [1]   CHRONIC MYELOGENOUS LEUKEMIA [1]   CLINICAL DISORDER [1]   CML [1]   DEATH [1]   DELETIONS [1]   DERMAL [1]   DISORDER [1]   DNA FRAGMENTATION [1]   ENDOMETRIAL CANCER [1]   ENDOREDUPLICATION [1]   HYPERPLASIA [1]   LEUKAEMIA [1]   LEUKEMIA [1]   MELANOMA [1]   MITOCHONDRIAL DYSFUNCTION [1]   MONOCYTIC LEUKEMIA [1]   NEURODEGENERATIVE DISORDER [1]   NSCLC [1]   OSTEOARTHRITIS [1]   RHEUMATOID ARTHRITIS [1]   SCARRING [1]   SENSITIVITY [1]   SKIN CANCER [1]   STEROID [1]   TUMOR CELL [1]   TUMOUR [1]   ALZHEIMER'S DISEASE [2]   CELL PROLIFERATION [2]   CYTOTOXIC [2]   RETINOBLASTOMA [2]   SUPPRESSION [3]   TUMOR [3]   APOPTOSIS [4]   CANCER [5]  
FERMENTATION [1]   SIGNALING PATHWAY [1]   G1 PHASE [2]   S PHASE [3]  
AKATERPIN [1]   CALYCULIN A [1]   FASCAPLYSIN [1]   VARIOLIN B [1]   VARIOLINS [1]  
ACETYLATED [1]   ACTIVATE [1]   ACTIVATED [1]   BLOCKED [1]   BLOCKING [1]   CLEAVAGE [1]   COMPLEX [1]   COMPLEXES [1]   CONTROL [1]   CONTROLLING [1]   DEPHOSPHORYLATE [1]   DEPOLYMERIZATION [1]   DERIVATIVE [1]   ENHANCED [1]   INACTIVATED [1]   INHIBITORY [1]   LIGAND [1]   LINK [1]   METABOLITE [1]   MODIFICATION [1]   MODULATION [1]   MUTATION [1]   PREVENT [1]   REDUCED [1]   REDUCTION [1]   REGULATION [1]   RIBOSYLATED [1]   SIGNALING [1]   SULFATE [1]   UPREGULATION [1]   CAUSE [2]   CAUSED [2]   INHIBITING [2]   PRODUCE [2]   REGULATE [2]   SUBSTRATE [2]   SUPPRESSED [2]   SYNTHESIZED [2]   TARGET [2]   TARGETED [2]   UPREGULATED [2]   ACTIVATION [3]   BINDING [3]   BLOCK [3]   DECREASED [3]   PRODUCTION [3]   INCREASE [4]   SYNTHESIS [4]   INCREASED [5]   INHIBITED [5]   ASSOCIATED [6]   INDUCE [6]   INDUCTION [6]   DECREASE [7]   EFFECT [7]   EXPRESSION [7]   INDUCED [7]   PRODUCT [7]   INHIBIT [8]   PHOSPHORYLATION [9]   KINASE [13]   INHIBITOR [16]  

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CYCLIN A -> 
  
4EBP1 [1]   AKT [1]   AMPK [1]   ATAXIA TELANGIECTASIA MUTATED [1]   ATM [1]   BCL-2 [1]   CASPASE-3 [1]   CDC2 [1]   CDC25C [1]   CDK4 [1]   CYCLIN [1]   CYCLIN D1 [1]   CYCLIN-DEPENDENT KINASE 2 [1]   MANA [1]   MCL-1 [1]   MOLT [1]   MTOR [1]   P-GP [1]   P21 [1]   P38 [1]   P70S6K [1]   PC-3 [1]   PRB [1]   CDK2 [2]   CYCLIN B1 [2]   CYCLIN E [2]   P-GLYCOPROTEIN [2]   P53 [4]  
APOPTOSIS [1]   CELL PROLIFERATION [1]   COLORECTAL CANCER [1]   DNA DAMAGE [1]   HEPATOCELLULAR CARCINOMA [1]   LEUKEMIA [1]   LUNG CANCER [1]   NSCLC [1]   PROSTATE CANCER [1]   SENSITIVITY [1]   STEROID [1]   STRESS [1]   TETRAPLOIDY [1]   TUMOR [1]   DEATH [2]   SUPPRESSION [2]   CANCER [4]  
S PHASE [1]   SIGNALING PATHWAY [1]  
ACTIVATION [1]   ASSEMBLY [1]   ASSOCIATED [1]   BINDING [1]   BLOCK [1]   CAUSE [1]   DECREASE [1]   DECREASED [1]   DEPOLYMERIZATION [1]   DERIVATIVE [1]   DOWNREGULATION [1]   INCREASE [1]   INDUCE [1]   INHIBIT [1]   INHIBITED [1]   INHIBITOR [1]   INHIBITORY [1]   KINASE [1]   MEDIATED [1]   MODULATION [1]   POLYMERIZATION [1]   PREVENTING [1]   REGULATION [1]   SIGNALING [1]   STIMULATED [1]   SUBSTRATE [1]   SYNTHESIS [1]   TARGET [1]   BLOCKED [2]   EFFECT [2]   INDUCTION [2]   PHOSPHORYLATION [2]   CAUSED [3]   EXPRESSION [3]   INDUCED [3]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


CYCLIN B1 -> 
  
4EBP1 [1]   AMPK [1]   C-JUN [1]   CASPASE-9 [1]   CYCLIN [1]   CYCLIN D1 [1]   CYTOCHROME C [1]   DR4 [1]   ERK [1]   HTERT [1]   IAP [1]   INTEGRIN [1]   JNK [1]   MOLT [1]   MTOR [1]   NANOS1 [1]   P38 [1]   P70S6K [1]   PARP [1]   PGC [1]   PI3K [1]   PROTEIN KINASE [1]   RAS [1]   TUMOR NECROSIS FACTOR [1]   AKT [2]   BCL-2 [2]   CASPASE-3 [2]   CDK2 [2]   CYCLIN A [2]   P21 [2]   P53 [2]   PTX-2 [2]   BAX [3]   CDC25C [3]   CELL CYCLE REGULATORY PROTEIN [3]   CDC2 [4]  
ADRENAL CARCINOMA [1]   CELL PROLIFERATION [1]   CYTOTOXIC [1]   DEATH [1]   DNA FRAGMENTATION [1]   ECTOPIC [1]   LEUKEMIA [1]   LUNG CANCER [1]   MELANOMA [1]   MITOCHONDRIAL DYSFUNCTION [1]   TETRAPLOIDY [1]   ENDOREDUPLICATION [2]   SUPPRESSION [2]   CANCER [3]   APOPTOSIS [5]  
M PHASE [1]   SIGNAL TRANSDUCTION [1]   TRANSLATION [1]   SIGNALING PATHWAY [3]  
ACTIVATE [1]   ASSEMBLY [1]   ASSOCIATE [1]   ASSOCIATION [1]   BINDING [1]   BLOCKED [1]   CLEAVAGE [1]   DECREASED [1]   DEGRADATION [1]   INHIBITED [1]   INTERFERING [1]   LIGAND [1]   METABOLITE [1]   MODULATION [1]   PHOSPHORYLATED [1]   PREVENT [1]   PREVENTING [1]   PRODUCE [1]   PRODUCTION [1]   REDUCTION [1]   REGULATED [1]   REGULATION [1]   REPRESS [1]   REPRESSION [1]   REPRESSOR [1]   SIGNAL [1]   STIMULATE [1]   SUPPRESSED [1]   TARGET [1]   TARGETED [1]   TRIGGER [1]   BLOCK [2]   CAUSE [2]   CAUSED [2]   CONTROL [2]   DEPOLYMERIZATION [2]   INCREASED [2]   INDUCED [2]   MEDIATED [2]   PHOSPHORYLATION [2]   SIGNALING [2]   UPREGULATED [2]   ACTIVATION [3]   DECREASE [3]   INDUCE [3]   INDUCTION [3]   INHIBIT [3]   INHIBITOR [3]   KINASE [3]   EXPRESSION [4]   INCREASE [4]   ASSOCIATED [5]   EFFECT [5]  

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