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Dictionaries: Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Human Genes+Proteins ( 0 1 2 3 4 5 6 7 8 9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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C

CARTILAGE MATRIX PROTEIN -> 
  
CMP [1]   IHH [1]   INDIAN HEDGEHOG [1]   MATRILIN-1 [1]   PER1 [1]   PER2 [1]  
OSTEOARTHRITIS [1]   SHOCK [1]   STRESS [1]  
ASSOCIATED [1]   CONTROL [1]   DOWNREGULATION [1]   EXPRESSION [1]   METABOLISM [1]  

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CARTILAGE OLIGOMERIC MATRIX PROTEIN -> 
  
AGGRECAN [1]   PGS [1]   PROTEOGLYCAN [1]  
JOINT DISEASE [1]   TYPE II [1]  
EXPRESSION [1]   INCREASED [1]   SULFATE [1]  

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CASEIN -> 
  
ALBUMIN [1]   INSULIN [1]   MATRIX METALLOPROTEINASE-1 [1]   MMP-1 [1]   ORNITHINE AMINOTRANSFERASE [1]   BETA-CASEIN [2]   PROTEASE [4]  
ABERRATION [1]   ALCOHOL [1]   BURN [1]   COLLAPSE [1]   DEPRIVATION [1]   DERMAL [1]   GUINEA [1]   INFILTRATION [1]   LATENT [1]   MORPHOLOGY [1]   NEOVASCULARIZATION [1]   NIGRA [1]   NITROGEN RETENTION [1]   ORAL [1]   PREMATURE [1]   PVC [1]   RETENTION [1]   STRESS [1]   TRANSPLANTATION [1]   TRAUMA [1]   WOUND [2]  
FERMENTATION [1]   PROTEOLYSIS [1]  
BINDING [1]   CATABOLISM [1]   CONVERSION [1]   COUPLED [1]   EFFECT [1]   ELEVATED [1]   ENHANCE [1]   ENHANCED [1]   EXPRESSION [1]   INHIBITOR [1]   INTERACTION [1]   MEDIATE [1]   METABOLISM [1]   OXIDIZED [1]   PREVENT [1]   REDUCING [1]   REDUCTION [1]   REGULATE [1]   REGULATION [1]   SULFATE [1]   SYNTHESIZED [1]   AFFECT [2]   ASSOCIATED [2]   DECREASE [2]   DEGRADE [2]   DEGRADED [2]   INCREASE [2]   REDUCED [2]   CONTROL [3]   DECREASED [3]   DEGRADATION [3]   INCREASED [3]   INHIBITED [3]   PRODUCTION [3]   SUBSTRATE [3]   SYNTHESIS [5]  

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CASEIN KINASE -> 
  
AXIN [1]   WNT [1]  
ALCOHOL [1]   ANGIOGENESIS [1]   HISTOLOGY [1]   INJURY [1]   MYOCARDIAL INFARCTION [1]   WOUND [1]  
CONTROL [1]   DECREASED [1]   DEGRADATION [1]   EFFECT [1]   ENHANCE [1]   INCREASED [1]   INDUCED [1]   INHIBIT [1]   INHIBITOR [1]   REDUCED [1]   SIGNALING [1]   TARGET [1]  

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CASEIN KINASE 1 -> 
  
CDK2 [1]   CDK5 [1]   CK1 [1]   CYCLIN [1]   GLYCOGEN SYNTHASE KINASE [1]   GSK-3 [1]   GSK-3BETA [1]   MAP-1B [1]   PAK1 [1]   PROTEIN KINASE [1]   PROTEIN TAU [1]  
ALZHEIMER'S DISEASE [1]   NEURODEGENERATIVE DISORDER [1]  
BINDING [1]   BLOCK [1]   COMPLEX [1]   INHIBIT [1]   INHIBITOR [1]   KINASE [1]   LINK [1]   PHOSPHORYLATION [1]   PRODUCT [1]   REGULATE [1]  

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CASP2 -> 
  
ARRDC3 [1]   CASPASE-2 [1]   MIR-183 [1]   MIR-96 [1]   NEUROD4 [1]  
ACUTE [1]   RETINAL DEGENERATION [1]  
DISRUPTED [1]   ENHANCED [1]   EXPRESSION [1]   INCREASED [1]   REDUCED [1]   TARGET [1]  

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CASPASE 12 -> 
  
ANNEXIN V [1]   EEF2 [1]   EIF2 [1]   EIF2ALPHA [1]   PKR [1]   PROTEIN KINASE [1]  
APOPTOSIS [1]   CANCER [1]   COLORECTAL CANCER [1]   CYTOTOXIC [1]   GLIOMA [1]   STRESS [1]  
EUKARYOTIC TRANSLATION INITIATION [1]   TRANSLATION [1]  
EFFECT [1]   EXPRESSION [1]   INDUCED [1]   INDUCTION [1]   INHIBIT [1]   INHIBITED [1]   INHIBITOR [1]   PHOSPHORYLATION [1]   PREVENT [1]   PREVENTED [1]   SYNTHESIS [1]   TARGET [1]   TRIGGER [1]  

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CASPASE-2 -> 
  
ARRDC3 [1]   CASP2 [1]   MIR-183 [1]   MIR-96 [1]   NEUROD4 [1]  
ACUTE [1]   RETINAL DEGENERATION [1]  
DISRUPTED [1]   ENHANCED [1]   EXPRESSION [1]   INCREASED [1]   REDUCED [1]   TARGET [1]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


CASPASE-3 -> 
  
ACID SPHINGOMYELINASE [1]   ACTIVATOR PROTEIN 1 [1]   ADHESION MOLECULE [1]   AKT [1]   ALG-2 [1]   AMPK [1]   ANNEXIN V [1]   AP-1 [1]   ATAXIA TELANGIECTASIA MUTATED [1]   ATM [1]   BAK [1]   BCL-XL [1]   C-JUN [1]   CDC25C [1]   CELL CYCLE REGULATORY PROTEIN [1]   CIAP-2 [1]   COX [1]   COX-1 [1]   CYCLIN [1]   CYCLIN A [1]   CYCLIN E [1]   CYCLIN-DEPENDENT KINASE 2 [1]   CYCLOOXYGENASE-2 [1]   CYSTEINE PROTEASE [1]   DR4 [1]   EGR-1 [1]   FASL [1]   GADD45A [1]   HEK [1]   HTERT [1]   IGF2R [1]   INSULIN-LIKE GROWTH FACTOR [1]   JNK [1]   JUND [1]   MAMMALIAN TARGET OF RAPAMYCIN [1]   MANA [1]   MAP2K5 [1]   MCL-1 [1]   MTOR [1]   NAG-1 [1]   P-GLYCOPROTEIN [1]   P-GP [1]   P27KIP1 [1]   P73 [1]   PC-3 [1]   PCNA [1]   PI3K [1]   PLC [1]   PRB [1]   PROLIFERATING CELL NUCLEAR ANTIGEN [1]   PROTEIN KINASE [1]   RAPTOR [1]   SMASE [1]   STC [1]   SUPPRESSION OF TUMORIGENICITY [1]   TELOMERASE REVERSE TRANSCRIPTASE [1]   THROMBOSPONDIN-1 [1]   TNFAIP3 [1]   TSP1 [1]   TUMOR NECROSIS FACTOR [1]   TUMOR SUPPRESSOR PROTEIN [1]   VASCULAR ENDOTHELIAL GROWTH FACTOR [1]   XIAP [1]   CASPASE-8 [2]   CDC2 [2]   CDK2 [2]   CYCLIN B1 [2]   CYTOCHROME C [2]   ERK [2]   FAS [2]   IAP [2]   P21 [2]   PROTEASE [2]   PTX-2 [2]   VEGF [2]   P53 [3]   POLY(ADP-RIBOSE) POLYMERASE [3]   PARP [4]   CASPASE-9 [5]   BAX [9]   BCL-2 [10]  
ACUTE [1]   CELL TRANSFORMATION [1]   DERMAL [1]   ENDOREDUPLICATION [1]   GENOMIC INSTABILITY [1]   HEPATOCARCINOMA [1]   INJURY [1]   MITOCHONDRIAL DYSFUNCTION [1]   MORPHOLOGY [1]   MOUSE NEUROBLASTOMA [1]   NEOVASCULARIZATION [1]   NEUROBLASTOMA [1]   OXIDATIVE STRESS [1]   SHOCK [1]   SKIN CANCER [1]   SKIN MELANOMA [1]   SOLID TUMOR [1]   STARVATION [1]   THERAPEUTICS [1]   TUMOUR CELL [1]   TYPE I [1]   ANGIOGENESIS [2]   COLON CANCER [2]   COLORECTAL CANCER [2]   CYTOTOXIC [2]   HEPATOCELLULAR CARCINOMA [2]   MELANOMA [2]   PROSTATE CANCER [2]   SCID [2]   STRESS [2]   TOXICITY [2]   TUMOR [2]   TUMOR CELL [2]   CELL PROLIFERATION [3]   DNA DAMAGE [3]   DNA FRAGMENTATION [6]   LEUKEMIA [6]   CANCER [7]   DEATH [11]   APOPTOSIS [19]  
DNA REPLICATION [1]   M PHASE [1]   SIGNALING PATHWAY [1]   G1 PHASE [2]  
HEMIASTERLIN [1]   JASPLAKINOLIDE [1]   RHIZOCHALIN [1]  
ASSOCIATION [1]   BINDING [1]   CAUSE [1]   CLEAVED [1]   COMPLEX [1]   CONTROLLED [1]   DERIVATIVE [1]   DISRUPTION [1]   DOWNREGULATE [1]   DOWNREGULATION [1]   ENHANCE [1]   ENHANCED [1]   INTERACTION [1]   LIGAND [1]   LINK [1]   MEDIATE [1]   MEDIATED [1]   MUTATION [1]   PRODUCT [1]   RECRUITMENT [1]   REDUCED [1]   REGULATED [1]   SIGNALING [1]   STIMULATED [1]   STIMULATION [1]   SUPPRESS [1]   SUPPRESSED [1]   SYNTHESIS [1]   SYNTHESIZED [1]   BLOCKED [2]   DEGRADATION [2]   DEPOLYMERIZATION [2]   ELEVATED [2]   MODULATION [2]   POLYMERIZATION [2]   PREVENT [2]   PREVENTED [2]   REDUCTION [2]   SIGNAL [2]   UPREGULATED [2]   ACTIVATE [3]   ACTIVATED [3]   INHIBITORY [3]   KINASE [3]   TARGET [3]   UPREGULATION [3]   DECREASED [4]   PHOSPHORYLATION [4]   CAUSED [5]   SUBSTRATE [5]   DECREASE [7]   INCREASE [7]   INCREASED [7]   INHIBIT [7]   INHIBITED [8]   CLEAVAGE [9]   INDUCED [9]   INHIBITOR [9]   ASSOCIATED [10]   EFFECT [11]   ACTIVATION [12]   INDUCTION [12]   INDUCE [13]   EXPRESSION [14]  

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CASPASE 3 -> 
  
CASPASE 9 [1]   ERK [1]   EXTRACELLULAR SIGNAL-REGULATED KINASE 1 [1]   JNK [1]   MAP KINASE [1]   MATRIX METALLOPROTEINASE-2 [1]   NAC [1]   P38 [1]   P53 [1]   PARP [1]   PC-3 [1]   PP1 [1]   PP2A [1]   PROTEASE [1]   PROTEIN PHOSPHATASE [1]   SERINE/THREONINE PHOSPHATASE [1]   SERINE/THREONINE PROTEIN PHOSPHATASE [1]   TAT [1]   TRANSFERRIN RECEPTOR [1]   UROKINASE [1]   PCNA [2]   PROLIFERATING CELL NUCLEAR ANTIGEN [2]   ANNEXIN V [3]  
ANGIOGENESIS [1]   CHEMOTHERAPY [1]   COLON CANCER [1]   DNA DAMAGE [1]   MALIGNANCY [1]   METASTASES [1]   METASTATIC DISEASE [1]   OXIDATIVE STRESS [1]   PROMYELOCYTIC LEUKEMIA [1]   PROSTATE CANCER [1]   TUMOR [1]   TUMOR CELL [1]   CANCER [3]   DNA FRAGMENTATION [3]   LEUKEMIA [3]   SUPPRESSION [3]   CYTOTOXIC [4]   DEATH [4]   APOPTOSIS [7]  
SIGNALING PATHWAY [2]  
CALYCULIN A [1]   NAAMIDINE A [1]   OKADAIC ACID [1]  
ACTIVATE [1]   ASSOCIATED [1]   BLOCKING [1]   CHELATION [1]   DECREASED [1]   DISRUPTION [1]   ELEVATION [1]   INDUCER [1]   INDUCTION [1]   INHIBITED [1]   METABOLITE [1]   PRODUCING [1]   REGULATION [1]   SIGNAL [1]   SIGNALING [1]   SUPPRESSED [1]   TRIGGERED [1]   BINDING [2]   DECREASE [2]   DERIVATIVE [2]   ENHANCED [2]   MEDIATED [2]   PRODUCT [2]   PRODUCTION [2]   TARGET [2]   CLEAVAGE [3]   EXPRESSION [3]   INCREASE [3]   INDUCE [3]   INDUCED [3]   INHIBIT [3]   INHIBITOR [4]   ACTIVATION [5]   EFFECT [5]  

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