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Dictionaries: Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Human Genes+Proteins ( 0 1 2 3 4 5 6 7 8 9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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I

IGF-2 -> 
  
INSULIN-LIKE GROWTH FACTOR [1]   SP1 [1]  
ANGIOGENESIS [1]   CANCER [1]   HYPOXIA [1]   METASTASIS [1]   ORAL [1]   PROSTATE CANCER [1]   SARCOMA [1]   TUMOR [1]   TUMOR CELL [1]  
ACCEPTED [1]   BINDING [1]   INDUCED [1]   INHIBIT [1]   SUPPRESSES [1]  

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IGF2R -> 
  
BAX [1]   BCL-2 [1]   CASPASE-3 [1]   GADD45A [1]   JUND [1]   MAP2K5 [1]   P73 [1]   PARP [1]   POLY(ADP-RIBOSE) POLYMERASE [1]   TNFAIP3 [1]  
APOPTOSIS [1]   DNA FRAGMENTATION [1]   LEUKEMIA [1]   MORPHOLOGY [1]   TOXICITY [1]   TUMOR CELL [1]  
CLEAVAGE [1]   EFFECT [1]   EXPRESSION [1]   INDUCE [1]   INDUCED [1]   INHIBIT [1]   INHIBITED [1]   INHIBITORY [1]  

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IGFBP -> 
  
AMELOGENIN [1]   FSH [1]   GROWTH HORMONE [1]   IGF-1 [1]   IGFBP-3 [1]   IGFBP-4 [1]   VASCULAR ENDOTHELIAL GROWTH FACTOR [1]   VEGF [1]   IGFBP-2 [2]   IGFBP-5 [2]   INSULIN [2]   VITRONECTIN [2]   INSULIN-LIKE GROWTH FACTOR [3]  
AGGRESSIVE BEHAVIOR [1]   AGGRESSIVE CANCER [1]   ANGIOGENESIS [1]   ATRESIA [1]   CANCER [1]   DEFECT [1]   EOE [1]   ESTROGENIC [1]   NEUROBLASTOMA [1]   OVULATION [1]   PGA [1]   STEROID [1]   TUMORIGENESIS [1]   TYPE I [1]   CELL PROLIFERATION [2]  
ACTIVATE [1]   ACTIVATED [1]   ACTIVATION [1]   ACTIVATOR [1]   ALTER [1]   ASSOCIATED [1]   ATTACHED [1]   ATTACHMENT [1]   COMPLEX [1]   COMPLEXES [1]   DECREASE [1]   DECREASED [1]   INTERACTION [1]   MEDIATED [1]   MODIFICATION [1]   MODULATE [1]   REGULATION [1]   SECRETE [1]   SECRETED [1]   BOUND [2]   EFFECT [2]   ENHANCE [2]   ENHANCED [2]   INCREASED [2]   BINDING [3]   CONTROL [3]   EXPRESSION [3]   INCREASE [3]  

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IGFBP-2 -> 
  
GNRH [1]   IGFBP-4 [1]   IGFBP-5 [1]   INSULIN-LIKE GROWTH FACTOR [1]   VASCULAR ENDOTHELIAL GROWTH FACTOR [1]   VEGF [1]   IGFBP [2]  
AGGRESSIVE BEHAVIOR [1]   AGGRESSIVE CANCER [1]   ANGIOGENESIS [1]   CANCER [1]   FOLLICULOGENESIS [1]   NEUROBLASTOMA [1]   TUMORIGENESIS [1]   TYPE I [1]   ATRESIA [2]  
ACTIVATE [1]   ACTIVATED [1]   ACTIVATION [1]   ACTIVATOR [1]   DECREASE [1]   EFFECT [1]   ENHANCE [1]   INCREASE [1]   REDUCED [1]   REGULATE [1]   REGULATED [1]   REGULATION [1]   SECRETED [1]   STIMULATE [1]   ASSOCIATED [2]   BINDING [2]   INCREASED [2]   MEDIATED [2]   CONTROL [3]   EXPRESSION [3]  

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IGFBP-3 -> 
  
AMELOGENIN [1]   IGFBP [1]   INSULIN-LIKE GROWTH FACTOR [1]   VITRONECTIN [1]  
CELL PROLIFERATION [1]   EOE [1]  
BINDING [1]   BOUND [1]   COMPLEX [1]   EFFECT [1]   ENHANCED [1]   EXPRESSION [1]   INTERACTION [1]   MODULATE [1]   SECRETE [1]  

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IGFBP-4 -> 
  
IGFBP [1]   IGFBP-2 [1]   IGFBP-5 [1]   INSULIN-LIKE GROWTH FACTOR [1]  
ATRESIA [1]  
ASSOCIATED [1]   BINDING [1]   CONTROL [1]   DECREASE [1]   EXPRESSION [1]   INCREASE [1]   INCREASED [1]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


IGFBP-5 -> 
  
IGFBP-2 [1]   IGFBP-4 [1]   INSULIN [1]   VITRONECTIN [1]   IGFBP [2]   INSULIN-LIKE GROWTH FACTOR [2]  
ATRESIA [1]   CELL PROLIFERATION [1]   DEFECT [1]   PGA [1]   TYPE I [1]  
ASSOCIATED [1]   ATTACHED [1]   ATTACHMENT [1]   BINDING [1]   BOUND [1]   COMPLEXES [1]   CONTROL [1]   DECREASE [1]   ENHANCE [1]   ENHANCED [1]   EXPRESSION [1]   INCREASED [1]   MODIFICATION [1]   INCREASE [2]  

[draw networkshow hypotheses |   download as table: incl. pmid  excl. pmid]


IGF-II -> 
  
72 KDA GELATINASE [1]   PROTEASE [1]   STZ [1]   INSULIN-LIKE GROWTH FACTOR [2]  
ALCOHOL [1]   ANGIOGENESIS [1]   DEFICIENCY [1]   DIABETES [1]   DIABETES MELLITUS [1]   DIABETIC [1]   IMPAIRED WOUND HEALING [1]   WOUND [2]  
BINDING [1]   CAUSE [1]   DECREASE [1]   EFFECT [1]   EXPRESSION [1]   INDUCED [1]   LIGAND [1]   PRODUCED [1]   PRODUCT [1]   REDUCED [1]   REDUCTION [1]   REGULATED [1]   SECRETE [1]   SYNTHESIS [1]   INCREASED [2]  

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IGF-I RECEPTOR -> 
  
GLUCOCORTICOID RECEPTOR [1]   INSULIN [1]   INSULIN-LIKE GROWTH FACTOR [1]  
ALCOHOL [1]   DIABETES [1]   DIABETES MELLITUS [1]   DIABETIC [1]   HYPERCORTISOLEMIA [1]   HYPERGLYCEMIA [1]   HYPERGLYCEMIC [1]   SUPPRESSION [1]   WOUND [1]  
ASSOCIATED [1]   BINDING [1]   CONTROL [1]   DECREASE [1]   EXPRESSION [1]   INDUCTION [1]   LIGAND [1]   REDUCED [1]  

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IG HEAVY CHAIN VARIABLE REGION -> 
  
ADHESION MOLECULE [1]   RECEPTOR TYROSINE KINASE [1]  
TRANSPLANTATION [1]  
CONTROL [1]   EXPRESSION [1]   UPREGULATED [1]  

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