Human Genes+ProteinsDisease Related ConceptsPathwaysSponge CompoundsMode of action
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ACTIVATEBCL-2
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2
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18202802
Induction of apoptosis by pectenotoxin-2 is mediated with the induction of DR4/DR5, Egr-1 and NAG-1, activation of caspases and modulation of the Bcl-2 family in p53-deficient Hep3B hepatocellular carcinoma cells.
21603866
The marine sponge toxin agelasine Bincreases the intracellular Ca(2+) concentration and induces apoptosis in human breast cancer cells (MCF-7).