Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:ACTIVATE CYTOTOXIC
Abstracts found:10

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PMIDTitleDisplay
11962513 The novel cytotoxic sponge metabolite peloruside A, structurally similar to bryostatin-1, has unique bioactivity independent of protein kinase C.  
15870701 Oocyte-based screening of cytokinesis inhibitors and identification of pectenotoxin-2 that induces Bim/Bax-mediated apoptosis in p53-deficient tumors.  
15958059 Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products.  
17456040 PLA2 mediated arachidonate free radicals: PLA2 inhibition and neutralization of free radicals by anti-oxidants--a new role as anti-inflammatory molecule.  
17548137 A single intranasal immunization with inactivated influenza virus and alpha-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system.  
20161972 Geoditin A induces oxidative stress and apoptosis on human colon HT29 cells.  
20920557 Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway.  
22264149 Geopyxins A-E, ent-kaurane diterpenoids from endolichenic fungal strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: structure-activity relationships of geopyxins and their analogues.  
23132899 Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.  
2783923 Recruitment and activation of tumor-specific immune T cells in situ: functional studies using a sponge matrix model.  

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