Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:ACTIVATE METABOLITE
Abstracts found:8

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PMIDTitleDisplay
11600145 Effects of marine sponge extracts on mitogen-activated protein kinase (MAPK/ERK(1,2)) activity in SW-13 human adrenal carcinoma cells.  
11962513 The novel cytotoxic sponge metabolite peloruside A, structurally similar to bryostatin-1, has unique bioactivity independent of protein kinase C.  
16643023 Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-gamma (PPARgamma): the marine sponge metabolite psammaplin A activates PPARgamma and induces apoptosis in human breast tumor cells.  
17088975 Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors.  
17140562 Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway.  
17456040 PLA2 mediated arachidonate free radicals: PLA2 inhibition and neutralization of free radicals by anti-oxidants--a new role as anti-inflammatory molecule.  
19262557 A sesquiterpene quinone, dysidine, from the sponge Dysidea villosa, activates the insulin pathway through inhibition of PTPases.  
2881714 Metabolism of some carcinogenic aromatic amines in four species of marine sponges.  

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