Human Genes+ProteinsDisease Related ConceptsPathwaysSponge CompoundsMode of action
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ACTIVATIONDEPOLYMERIZATION
Abstracts found:
3
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1
PMID
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18571148
Induction of G2/M arrest, endoreduplication, and apoptosis by actin depolymerization agent pextenotoxin-2 in human leukemia cells, involving activation of ERK and JNK.
18663430
Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damagestress.
19857460
Calyculin A-induced neurite retraction is critically dependent on actomyosin activation but not on polymerization state of microtubules.