Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:ACTIVATION DOWNREGULATION
Abstracts found:9

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PMIDTitleDisplay
10445297 A homolog of the putative tumor suppressor QM in the sponge Suberites domuncula: downregulation during the transition from immortal to mortal (apoptotic) cells.  
16159871 Matrix embedding alters the immune response against endothelial cells in vitro and in vivo.  
17356266 Induction of apoptosis by (Z)-stellettic acid C, an acetylenic acid from the sponge Stelletta sp., is associated with inhibition of telomerase activity in human leukemic U937 cells.  
18663430 Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress.  
19189070 NF-kappaB blockade upregulates Bax, TSP-1, and TSP-2 expression in rat granulation tissue.  
20173740 miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis.  
21730286 MicroRNA-146a inhibits glioma development by targeting Notch1.  
22685542 microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion.  
22879939 TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion.  

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