Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:BINDING KINASE
Abstracts found:14

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PMIDTitleDisplay
10662688 Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent.  
10973815 Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.  
12939464 Naamidine A intensifies the phosphotransferase activity of extracellular signal-regulated kinases causing A-431 cells to arrest in G1.  
15923643 Innate immune defense of the sponge Suberites domuncula against bacteria involves a MyD88-dependent signaling pathway. Induction of a perforin-like molecule.  
16415178 The microtubule binding drug laulimalide inhibits vascular endothelial growth factor-induced human endothelial cell migration and is synergistic when combined with docetaxel (taxotere).  
17140562 Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway.  
17190971 Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).  
19445900 The inhibition of TNF-alpha-induced NF-kappaB activation by marine natural products.  
20453877 Functional transition of Pak proto-oncogene during early evolution of metazoans.  
21244636 Structural features underlying selective inhibition of GSK3β by dibromocantharelline: implications for rational drug design.  

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