Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:CYCLIN INHIBITOR
Abstracts found:16

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PMIDTitleDisplay
10662688 Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent.  
11072253 Mechanism of action of aragusterol a (YTA0040), a potent anti-tumor marine steroid targeting the G(1) phase of the cell cycle.  
11597488 Coscinosulfate, a CDC25 phosphatase inhibitor from the sponge Coscinoderma mathewsi.  
12965186 Calyculin A causes the activation of histone H1 kinase and condensation of chromosomes in unfertilized sea urchin eggs independently of the maturation-promoting factor.  
14974610 Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A.  
15057141 Smenospongine, a spongean sesquiterpene aminoquinone, induces erythroid differentiation in K562 cells.  
16163705 Ircinin-1 induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells.  
16176456 Recombinant adenovirus-p21 attenuates proliferative responses associated with excessive scarring.  
16181779 Variolin B and its derivate deoxy-variolin B: new marine natural compounds with cyclin-dependent kinase inhibitor activity.  
16786142 Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB phosphorylation.  

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