Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:EFFECT POLYMERIZATION
Abstracts found:43

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PMIDTitleDisplay
7961961 Mycalolide B, a novel actin depolymerizing agent.  
8195116 Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.  
8232226 Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.  
8555181 Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.  
8646787 Effects of latrunculin A on immunological phagocytosis and macrophage spreading-associated changes in the F-actin/G-actin content of the cells.  
8853557 Cellular changes of rat embryonic fibroblasts by an actin-polymerization inhibitor, bistheonellide A, from a marine sponge.  
8886501 A family of novel actin-inhibiting marine toxins.  
9210394 Mode of inhibition of HIV reverse transcriptase by 2-hexaprenylhydroquinone, a novel general inhibitor of RNA-and DNA-directed DNA polymerases.  
9288783 Microfilament depletion and circumvention of multiple drug resistance by sphinxolides.  
9380024 The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.  

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