Database Summary
  Description:
  Selected dictionaries: Human Genes+Proteins  Disease Related Concepts  Pathways  Sponge Compounds  Mode of action 

Searching for:INHIBITORY KINASE
Abstracts found:16

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PMIDTitleDisplay
11597488 Coscinosulfate, a CDC25 phosphatase inhibitor from the sponge Coscinoderma mathewsi.  
11784156 Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1).  
14612527 Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.  
15123286 Synthesis and target identification of hymenialdisine analogs.  
15958059 Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products.  
16415178 The microtubule binding drug laulimalide inhibits vascular endothelial growth factor-induced human endothelial cell migration and is synergistic when combined with docetaxel (taxotere).  
17140562 Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway.  
17708655 Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease.  
18663430 Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress.  
18676149 Nakijiquinones G-I, new sesquiterpenoid quinones from marine sponge.  

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